Bodybuilders often take HGH in exogenous form to increase HGH production, increasing muscle mass and fat loss. It was originally thought that increasing HGH intake was anabolic because the increased hormone level produced by taking exogenous forms of HGH would have the same effects as the increases experienced with the ingestion of its own natural forms, i.e., from foods like fish oil and casein.
However, when the body’s production of the naturally occurring endogenous HGH levels is increased, a greater increase in muscle mass and fat loss occurs. This has led to the idea that exogenous androgens may contribute to weight gain and muscle mass loss through different mechanisms, hgh lilly.
If muscle gain of up to 4 lb per week as a result of exogenous androgens in the diet were the only mechanism, then no increase in diet-induced exogenous androgens would be needed. Thus, when HGH administration (in the form of exogenous testosterone) is given to men, the level of free testosterone (the metabolite of the active androgen testosterone) is increased substantially (1,2). A possible explanation for this was the assumption that these androgens are “bound at the site of action” and that this could explain the increased level of free testosterone after HGH administration, bulking fibers.
In contrast, when it became apparent that the effects of exogenous androgens on body fat and energy expenditure were different, the androgen action hypothesis was abandoned. In fact, the metabolic and physiologic basis for the apparent differences between androgens from endogenous androgens via increases in free testosterone (which binds and stimulates testosterone-induced oxidation of fatty acids) and decreases in total and free testosterone (which inhibits testosterone-induced oxidation of fatty acids) can be explained, at least in part, by the actions of endogenous androgens (which are not affected by the changes in the level of the free androgen) with respect to their effects on HGH production, lilly hgh. It seems that in order for the metabolic and physiologic effects of exogenous androgens to be relevant, some of the androgen-dependent aspects of the HGH action must exist.
In fact, although the endogenous androgen testosterone-induced increase in muscle mass and fat loss could contribute to an increased response to exogenous androgens (as discussed above), some of the metabolic measures (including fatty acid oxidation) would also increase, discount supplement stacks. This finding indicates that the level of free androgen in the human body has a much smaller influence on these metabolic responses than previously believed.
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